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Strength
Pack Size
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ma213 Premarin (Cenestin, Enjuvia, Ogen, Generic Conjugated Estrogen)
Wyeth
0.625mg tabs
56
(2 x 28)
93.61
use
ma218
ma219
ma220
1786 Premarin (Cenestin, Enjuvia, Ogen, Generic Conjugated Estrogen)
SPECIAL OFFER - SAVE NOW
Wyeth
0.625mg tabs
168
(6 x 28)
250.00
use
ma218
ma219
ma220
ma214 Premarin (Cenestin, Enjuvia, Ogen, Generic Conjugated Estrogen)
Please use ma218/ 219/ 220
Wyeth
1.25mg tabs
56
(2 x 28)
128.21
out of stock
1787 Premarin Cream (Conjugated Estrogen Cream)
Wyeth
0.625mg/ gm cream
42.5 gm
91.58
ma215 Premarin (Cenestin, Enjuvia, Ogen, Gynodiol, Femtrace, Menest, Generic Estrogen)
Wyeth
0.3mg
84 tabs
38.67
ma216 Premarin (Cenestin, Enjuvia, Ogen, Gynodiol, Femtrace, Menest, Generic Estrogen) 
Wyeth
0.625mg
84 tabs
40.70
out of stock
ma217 Premarin (Cenestin, Enjuvia, Ogen, Gynodiol, Femtrace, Menest, Generic Estrogen) 
Wyeth
1.25mg
84 tabs
54.95
out of stock

ma218
Estrin (Cenestin, Enjuvia, Ogen, Premarin, Generic Conjugated Estrogen)
Cipla
0.625mg
30 tabs
39.75

ma219
Estrin (Cenestin, Enjuvia, Ogen, Premarin, Generic Conjugated Estrogen)
Cipla
0.625mg
90 tabs
(3 x 30)
102.00

ma220
Estrin (Cenestin, Enjuvia, Ogen, Premarin, Generic Conjugated Estrogen)
Cipla
0.625mg
180 tabs
(6 x 30)
167.00

General Description & Use
A powerful and effective female hormone used as Hormone replacement Therapy (HRT) for symptoms associated with menopause: hot flashes, sweating, sleep disturbance, vaginal discomfort (dryness and itchiness), poor concentration, and irritability. Used in the treatment of breast cancer in post menopausal women and breast and prostate cancer.

Note: Premarin 1.25mg tablets have now been discontinued. We are advising customers who were taking the 1.25mg dosage to now order the 0.625mg Tablets and take two tablets at your scheduled dosage time.

PREMARIN® is also a popular female hormone for M2F transsexuals in gender reassignment

Premarin is manufactured by Wyeth PharmaceuticalsPREMARIN® is the commercial name for compound drug consisting primarily of conjugated estrogens. Isolated from mare's urine (PREgnant MARes' urINe), it is manufactured by Wyeth Pharmaceuticals and has been marketed since 1942. It is available in oral (0.3/ 0.45/ 0.625/ 1.25mg), IV, and topical form.

Buy Premarin Conjugated EstrogensThe major forms of estrogen in PREMARIN® are estrone (>50%), equilin (15-25%) and equilenin. The estrogens in Premarin are often called "conjugated equine estrogens" (CEE) because the estrogen molecules are generally present with hydrophilic side-groups attached such as sulfate. Thus, estrone sulfate is actually the major molecule in PREMARIN®. Estrone sulfate is easily absorbed into the blood after PREMARIN® tablets are taken by women. Estrone sulfate is converted to estradiol, an active estrogen normally found in women. It is not clear if estrogens such as equilin that are foreign to the human body have effects in women that are significantly different from the estrogens like estradiol that are normally made in the human body.

As PREMARIN® is not a single compound, but a mixture of many naturally derived compounds, the structural diagram above does not show PREMARIN® but its primary ingredient, Estrone in its sulfated form. Thus, PREMARIN® cannot be characterized by the structure of just one of its many compounds.

PREMARIN® (conjugated estrogens tablets, USP) is used after menopause to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce your chances of getting osteoporosis (thin weak bones).

PREMPRO® (conjugated estrogens/ medroxyprogesterone acetate tablets) is used after menopause in women with a uterus to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce your chances of getting osteoporosis (thin weak bones).

Buy Premarin CreamPREMARIN® (conjugated estrogens) Vaginal Cream is used after menopause to treat dryness, itching, and burning, in and around the vagina. PREMARIN® and PREMPRO should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks. If using PREMARIN® or PREMPRO only to treat your symptoms of vaginal dryness, consider topical therapies first. If you do not have symptoms, non-estrogen treatments should be carefully considered before taking PREMARIN® and PREMPRO solely for the prevention of postmenopausal osteoporosis.

In a clinical trial, the most commonly reported (=5%) side effects that occurred more frequently with PREMARIN than with placebo were vaginitis due to yeast or other causes, vaginal bleeding, painful menstruation, and leg cramps.

In a clinical trial, the most commonly reported (=5%) side effects that occurred more frequently with PREMPRO 0.45 mg/1.5 mg and PREMPRO 0.625 mg/2.5 mg than with placebo were breast pain/enlargement, vaginitis due to yeast or other causes, leg cramps, vaginal spotting/bleeding, and painful menstruation. In a clinical trial, there was no difference in the commonly reported (=5%) side effects for women taking PREMPRO 0.3 mg/1.5 mg compared to those taking placebo.

The most commonly reported side effects of PREMARIN® Vaginal Cream include vaginal discomfort or pain, breast pain, vaginitis, and itching.

PREMARIN®, PREMPRO, and PREMARIN® Vaginal Cream should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack in the past year, have or had blood clots, have liver problems, are allergic to any of the ingredients in PREMARIN®, PREMPRO, or PREMARIN® Vaginal Cream, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

Hormone replacement therapy (HRT)
If severe side effects of low levels of estradiol in a woman's blood are experienced (commonly at the beginning of menopause or after oophorectomy), hormone replacement therapy may be prescribed. Often such therapy is combined with a progestin.

Estrogen therapy may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. Estrogen therapy is also used to maintain female hormone levels in male-to-female transsexuals.

Some further suggested female hormone medications supplied by NPD
The following are marketed versions of estradiol:

Oral versions: Estrace, Activella (also contains a progestin), estradiol acetate, Progynova, Estrofem®, Zumenon, Ethinylestradiol, Lynoral, Estinyl
Transdermal preparation: Alora, Climara, Vivelle, Vivelle-Dot, Menostar, Estraderm TTS
Ointments: Estrasorb Topical, Estrogel, Elestrin
Injection: Estradiol cyprionate: Lunelle monthly injection, Estradiol valerate

Also see a list of all hormones available from NPD here.

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